Carbon 1992.
| Methods | Randomized Multicenter | |
| Participants | Adults (mean age: 55) Hospitalized CAP (severe pneumonia excluded) | |
| Interventions | Atypical: PO temafloxacin 600 mg X 2/d Non‐atypical: PO amoxicillin 500 mg X 3/d | |
| Outcomes | Failure = persistence of symptoms or signs, treatment modification Modification = failure | |
| Notes | Severe pneumonia excluded | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Not described |
| Allocation concealment (selection bias) | Unclear risk | Not described |
| Incomplete outcome data (attrition bias) Mortality | Low risk | All patients evaluated |
| Incomplete outcome data (attrition bias) Failure | High risk | 243/246 patients evaluated |
| Selective reporting (reporting bias) | Low risk | Not identified |
| Other bias | High risk | Not ITT Sponsored |
| Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blind |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | Double‐blind |