Figure 5.

Plasma-conditioned Ringer’s lactate induced cell cycle arrest in pancreatic cancer cells alone or in combination with chemotherapy. (a,c,e,g) Representative overlays of flow cytometry data of DNA content, showing the amount of treated pancreatic cancer cells in the G1, S, and G2 phase of the cell cycle; (b,d,f,h) quantification of cells in cell cycle arrest (G2/G1 ratio) for MiaPaca cells in treatment regimen with (b) cisplatin or (d) gemcitabine, as well as PaTuS cells after exposure to respective treatment regimens with (f) cisplatin and (h) gemcitabine 48 h post-treatment. Data show the mean and are representatives from three independent experiments.