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. 2019 Dec 20;9(1):25. doi: 10.3390/cells9010025

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Differential expression of miRNA and mRNA in neuronal depolarization. (A) Volcano plot generated using fold change values and adjusted p-values [false discovery rate (FDR)] to compare the expression changes of miRNA and (B) mRNA between depolarized and resting cells. Red dots represent significant upregulation and green dots represent downregulation, with the vertical lines corresponding to 1.5-fold (miRNA) and two-fold (mRNA) change and the horizontal line representing an FDR cut off < 0.05.