Supplemental oxygen for the treatment of prethreshold retinopathy of prematurity

. 2003 Apr 22;2003(2):CD003482. doi: 10.1002/14651858.CD003482

Study	Reason for exclusion
Gaynon 1997	This was a non‐randomised retrospective cohort study. Oxygen saturation levels for infants with prethreshold ROP were increased in a stepwise fashion (target minimum 92%‐99%) over a number of years (1985‐1993). Patient allocation was not randomised and thus the study was excluded from the review.
Seiberth 1998	Preterm infants with stage 3 ROP between 1994 an 1996 were treated with supplemental oxygen to maintain pulse oximetry saturations above 98%. The incidence of threshold ROP was compared to a historical control group of preterm infants born between 1991 and 1993. Patients were not randomly allocated to a treatment and therefore this non‐randomised, retrospective cohort study was excluded from the review.

Study

Reason for exclusion

Gaynon 1997

This was a non‐randomised retrospective cohort study. Oxygen saturation levels for infants with prethreshold ROP were increased in a stepwise fashion (target minimum 92%‐99%) over a number of years (1985‐1993). Patient allocation was not randomised and thus the study was excluded from the review.

Seiberth 1998

Preterm infants with stage 3 ROP between 1994 an 1996 were treated with supplemental oxygen to maintain pulse oximetry saturations above 98%. The incidence of threshold ROP was compared to a historical control group of preterm infants born between 1991 and 1993. Patients were not randomly allocated to a treatment and therefore this non‐randomised, retrospective cohort study was excluded from the review.