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. 2020 Jan 14;12(1):208. doi: 10.3390/cancers12010208

Figure 2.

Figure 2

TMEM167A is overexpressed in gliomas and correlates inversely with tumor aggressiveness. Analysis of the amount of GOSR1 (A), TMEM167A (B), and STX17 (C) mRNAs levels in gliomas (LGG + GBM Rembrandt cohort) compared with normal tissue. (D–F) Kaplan–Meier overall survival curves of patients from the Rembrandt LGG + GBM cohort. Patients were separated on the basis of high and low GOSR1 (D), TMEM167A (E), and STX17 (F) gene expression values. (G) qRT-PCR analysis of TMEM167A in our own cohort of glioma samples (n = 52) compared with normal tissue. HPRT expression was used for normalization (H) Kaplan–Meier overall survival curves of patients from our own glioma cohort (n = 36). Patients in each cohort were stratified into 2 groups on the basis of high and low TMEM167A expression values. ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001.