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. 2020 Jan 17;12(1):229. doi: 10.3390/cancers12010229

Figure 1.

Figure 1

RASSF1A signalling is dependent on its level of expression and the stoichiometry of its complexes. As exemplified by the RASSF1A-scaffolded complex (blue and orange boxes), if there is no RASSF1A expression, or sub optimal expression, there is low complex formation and the signal will be low (left); in the case of intermediate RASSF1A expression, signal will be high (centre), this is the physiological range of expression; if there is too much RASSF1A the signal will be low (right).