Table A3.

Pre-stimulation activities of the in silico model as starting point for the therapy simulation.

Western Blot Data (in Comparison to Untreated Control)					Proliferation Value in 3D			Apoptosis in 3D Compared to Ctrl
	Ctrl	Gef	Vem	Gef+Vem			HROC87		HROC87
pEGFR	medium	↓↓	↓	↓↓	Ctrl		0.5	Ctrl	weak
pErk	strong	↓	↓	↓↓	Gef		0.5	Gef	↑
pHGFR	strong	↓	0	↓↓	Vem		0.5	Vem	↑
pAkt	weak	↓	0	↑	Gef + Vem		0.2	Gef+Vem	↑