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. 2019 Dec 24;9(1):58. doi: 10.3390/cells9010058

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Pancreatic ductal adenocarcinoma (PDAC) heterogeneity in Kras^G12D/+;LSL-Trp53^R172H/+;Pdx-1-Cre (KPC) mouse model. (A) Survival of KPC cohort (n = 46) with median survival of 160 days. (B) PDAC establishment histopathologically confirmed and respective tumors graded.