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. 2020 Jan 9;12(1):160. doi: 10.3390/cancers12010160

Table 5.

Significant predictors of concomitant distant metastases in prostate cancer patients—results of ROC analysis.

Parameter Sensitivity Specificity PPV NPV AUC (95% CI) Error Rate
≥4 CTCs (I) 0.500 0.986 0.900 0.885 0.760 (0.613–0.908) 0.114
PSA > 25ng/mL (II) 73.680 37.650 0.571 0.878 0.669 (0.508–0.829) 0.163
Gleason sum = 9 pts (III) 0.211 0.929 0.400 0.840 0.697 (0.570–0.825) 0.202
cT > 2c (IV) 0.737 0.595 0.292 0.909 0.666 (0.534–0.798) 0.379
D’Amico criteria = 3 0.316 0.964 0.667 0.862 0.729 (0.593–0.865) 0.155
I + II + III + IV 0.611 0.971 0.846 0.905 0.901 (0.810–0.993) 0.103

AUC—Area Under the Curve.