Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene

. Author manuscript; available in PMC: 2020 Feb 13.

Published in final edited form as: Stem Cell Res. 2018 Dec 26;34:101374. doi: 10.1016/j.scr.2018.101374

Resource Table.

Unique stem cell line identifier	TRNDi003-A
Alternative name(s) of stem cell line	HT215A
Institution	National Institutes of Health National Center for Advancing Translational Sciences Bethesda, Maryland, USA
Contact information of distributor	Dr. Wei Zheng Wei.Zheng@nih.gov
Type of cell line	iPSC
Origin	Human
Additional origin info	Age: 13-year-old Sex: Female Ethnicity: Somalian
Cell Source	Peripheral blood mononuclear cells (PBMCs)
Clonality	Clonal
Method of reprogramming	Integration-free Sendai viral vectors
Genetic Modification	NO
Type of Modification	N/A
Associated disease	Noonan syndrome with multiple lentigines (NSML)
Gene/locus	PTPN11^Q510P
Method of modification	N/A
Name of transgene or resistance	N/A
Inducible/constitutive system	N/A
Date archived/stock date	03-26-2017
Cell line repository/bank	Human Pluripotent Stem Cell Registry https://hpscreg.eu/cell-line/TRNDi003-A
Ethical approval	Completed under Boston Children’s Hospital IRB Protocol 08-05-0208