Table 4. Bioavailability and Drug Targeting Efficiency of Complement C5a Receptor 1 Antagonists.

drug	route	area under curve (min μg/mL)	bioavailability	brain drug targeting efficiency	spinal cord drug targeting efficiency
PMX53	i.v.	150.63	100%
	s.c.	134.45	85%	1.37	0.77
	i.p.	107.81	68.2%	0.71	0.63
	p.o.	13.64	8.6%	8.21	4.42
PMX205	i.v.	208.03	100%
	s.c.	201.04	96.6%	1.71	1.37
	i.p.	125.50	60.3%	1.88	0.71
	p.o.	47.12	22.6%	10.81	8.21