Table 2.

Correlation matrix of original and surrogate dataset

ORIGINAL	Pearson correlation coefficient
	Variables	SAA	CHIT1	AOPP	RSSP	age	BMI
	SAA	1.00	−0.01	− 0.01	0.15	0.02	0.23
	CHIT1	−0.01	1.00	0.00	0.28	0.40*	−0.01
	AOPP	−0.01	0.00	1.00	0.06	0.09	0.17
	RSSP	0.15	0.28	0.06	1.00	0.38*	0.09
	Age	0.02	0.40*	0.09	0.38*	1.00	0.14
	BMI	0.23	−0.01	0.17	0.09	0.14	1.00
	p-value
	Variables	SAA	CHIT1	AOPP	RSSP	age	BMI
	SAA	0.00	0.56	1.00	0.11	0.57	0.01
	CHIT1	0.56	0.00	0.87	0.00	0.00	0.86
	AOPP	1.00	0.87	0.00	0.69	0.45	0.10
	RSSP	0.11	0.00	0.69	0.00	0.00	0.59
	Age	0.57	0.00	0.45	0.00	0.00	0.28
	BMI	0.01	0.86	0.10	0.59	0.28	0.00
SURROGATE	Pearson correlation coefficient
	Variables	SAA	CHIT1	AOPP	RSSP	age	BMI
	SAA	1.00	−0.16	0.02	0.22	−0.02	−0.16
	CHIT1	−0.16	1.00	−0.03	−0.06	−0.08	0.06
	AOPP	0.02	−0.03	1.00	−0.12	0.06	−0.01
	RSSP	0.22	−0.06	−0.12	1.00	−0.18	0.09
	Age	−0.02	−0.08	0.06	−0.18	1.00	−0.10
	BMI	−0.16	0.06	−0.01	0.09	−0.10	1.00
	p-value
	Variables	SAA	CHIT1	AOPP	RSSP	age	BMI
	SAA	0.00	0.72	1.00	0.23	0.57	0.10
	CHIT1	0.72	0.00	0.88	0.02	0.00	1.00
	AOPP	1.00	0.88	0.00	0.66	0.61	0.20
	RSSP	0.23	0.02	0.66	0.00	0.02	0.58
	Age	0.57	0.00	0.61	0.02	0.00	0.28
	BMI	0.10	1.00	0.20	0.58	0.28	0.00

The first table shows the Pearson correlations coefficients and the p-values of our original dataset, the second table shows the Pearson correlations coefficients and the p-values of surrogate dataset

*indicates statistically significant values