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. 2020 Feb 12;21:50. doi: 10.1186/s12931-020-1310-9

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Panel (a) Change in FEV₁ and FVC after 4 weeks of oral prednisolone (30 mg/day) in female non-smoking COPD patients (open bars) or placebo (black bars); data are mean values ± SEM; NS = non-significant; Panel (b) Decline in post-bronchodilator FEV₁ between healthy (n = 88), smoking COPD (n = 44) and non-smoking COPD subjects (n = 62) over 2 years