Table 2.
Diversity and neutrality tests of the Pvmdr1 gene in P. vivax populations from different areas of the GMS
| Populations | SNP | No. of haplotypes | Haplotype diversity (Hd ± SD) | Nucleotide diversity | Neutrality tests | Rm | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| S | NS | θw | π | D | D* | F* | ||||
| China–Myanmar 2008 (n = 27) | 2 | 20 | 21 | 0.983 ± 0.014 | 0.0012 | 0.0010 | − 0.7839 | − 1.2499 | − 1.2950 | 4 |
| China–Myanmar 2012–2013 (n = 129) | 8 | 15 | 33 | 0.869 ± 0.023 | 0.0009 | 0.0009 | 0.0316 | 0.0357 | 0.0404 | 6 |
| China–Myanmar 2015 (n = 119) | 34 | 59 | 75 | 0.971 ± 0.008 | 0.0039 | 0.0012 | − 2.2310** | − 4.2879** | − 4.0776** | 15 |
| Central China (n = 55) | 7 | 17 | 23 | 0.914 ± 0.026 | 0.0010 | 0.0006 | − 1.1179 | − 2.1131 | − 2.0953 | 3 |
| Thailand–Myanmar (n = 69)a | 10 | 21 | 44 | 0.974 ± 0.009 | 0.0015 | 0.0009 | − 1.3670 | − 2.7450* | − 2.6640* | 5 |
| Thailand–Cambodia (n = 29)a | 7 | 7 | 15 | 0.926 ± 0.026 | 0.0008 | 0.0007 | − 0.4540 | − 0.9490 | − 0.9320 | 4 |
aAnalysis has been done in these populations on a near full-length Pvmdr1 gene (4264 bp)
Abbreviations: S, synonymous; NS, nonsynonymous; SD, standard deviation; D, Tajima’s D; D*, Fu & Li’s D*, F*: Fu & Li’s F*, Rm, minimum recombination events
*P < 0.05, **P < 0.02