| Methods |
Randomised controlled trial. Setting: inpatient |
| Participants |
39 opioid dependent, 31 males, mean age 27 years. EXC cr: previous detoxification treatments |
| Interventions |
(1) methadone 21 participants, starting dose 60 mg/day, tapered of 2.5‐5 mg/day; (2) buprenorphine, 18 participants, starting dose 12‐16 mg/day, tapered of 0.8‐1.2 mg/day. Scheduled duration of the study 28 days. Country of origin: Europe (Germany) |
| Outcomes |
Completion of treatment, withdrawal symptoms (OOWS), craving. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
method not reported |
| Allocation concealment (selection bias) |
Unclear risk |
method of allocation not reported |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
not reported |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
not reported |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
results on all randomised participants |
