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. 2013 Jun 4;2013(6):CD004874. doi: 10.1002/14651858.CD004874.pub4

Aurangzeb 2003.

Methods Randomised, non‐blinded controlled clinical trial
Participants Children between 3 to 72 months of age, admitted in the hospital with community‐acquired pneumonia
Interventions The patients were randomly allotted to 1 of the 3 groups
 Group 1 was given amoxycillin 75 mg/kg/d IV in 3 divided doses, Group 2 was given cefuroxime 75 mg/kg/d IV in 3 divided doses and Group 3 was given clarithromycin 15 mg/kg/d IV divided into 2 divided doses
Outcomes 1. Improvement defined as slower respiratory rate (either back to normal for the age of the child), or more than 5 as compared to the previous day evaluation without retractions. The same defined as still breathing fast as before as or higher than that with no chest in drawing or danger signs
2. Worse was defined as development of severe pneumonia or very severe disease
3. Cure was defined as return of respiratory rate to age specific normal range
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information provided
Allocation concealment (selection bias) Unclear risk No information provided
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Open‐label study
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Open‐label study
Selective reporting (reporting bias) Unclear risk There are discrepancies in the number of patients in different study arms
Incomplete outcome data (attrition bias) 
 All outcomes Low risk None
Other bias Unclear risk Source of funding not mentioned