| Methods |
RCT comparing co‐trimoxazole for 5 days and procaine penicillin single dose with ampicillin for 5 days |
| Participants |
Children 1 month to 4 years of age with non‐severe pneumonia |
| Interventions |
Daily co‐trimoxazole PO for 5 days or single‐dose procaine penicillin with daily PO ampicillin |
| Outcomes |
Cure rate, hospitalisation rate and death rate |
| Notes |
Exclusion criteria: very severe disease, refusal of consent, unable to take tablets |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Sequence generation and randomisation not clear |
| Allocation concealment (selection bias) |
High risk |
Eligible children were allocated sequentially to 2 treatment groups by study physician |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Open‐label study |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Open‐label study |
| Selective reporting (reporting bias) |
Unclear risk |
Data not recorded clearly |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Data not recorded clearly |
| Other bias |
Unclear risk |
Source of funding not mentioned |
