Methods |
RCT comparing amoxycillin and co‐amoxyclavulanic acid with amoxycillin alone in bacterial pneumonia (non‐severe) |
Participants |
Children aged 2 years to 12 years age, with non‐severe pneumonia |
Interventions |
Amoxycillin and co‐amoxyclavulanic acid (250 mg + 62.5 mg or 500 + 125 mg tds) with amoxycillin (250 mg or 500 mg tds) for 10 days |
Outcomes |
Poor or no response; cure rate |
Notes |
Exclusion criteria: renal/hepatic impairment; hypersensitivity to penicillin/cephalosporin |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Serial number selected on random basis |
Allocation concealment (selection bias) |
Unclear risk |
Not mentioned |
Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Unblinded study |
Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Unblinded study |
Selective reporting (reporting bias) |
Unclear risk |
No selective reporting |
Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Incomplete data adequately addressed |
Other bias |
Unclear risk |
Source of funding not mentioned |