| Methods |
RCT comparing cefpodoxime and co‐amoxyclavulanic acid in LRTI |
| Participants |
Children aged 3 months to 11.5 years |
| Interventions |
Cefpodoxime 5 to 12 mg/kg/day PO for 10 days or co‐amoxyclavulanic acid 6 to 13 mg/kg/day for 10 days |
| Outcomes |
Response rate |
| Notes |
Exclusion criteria: nosocomial infection, antibiotics in past 48 hours, allergy to beta‐lactam antibiotics, suspected/confirmed TB, congenital anomalies |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Information not provided |
| Allocation concealment (selection bias) |
Unclear risk |
No mention about details of allocation concealment |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
Information not provided |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Information not provided |
| Selective reporting (reporting bias) |
Unclear risk |
No intention‐to‐treat analysis. No details of children excluded from the analysis |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No intention‐to‐treat analysis. No details of children excluded from the analysis |
| Other bias |
Unclear risk |
Source of funding not mentioned |
