2. Search strategy EMBASE.

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#10 #9 not animal #9 #1 and #2 and #3 and #7 and #8 #8 (laparoscop*) #7 (colectom*) or (restorative proctocolectomy) or (surgery) or (resection) or (Total mesorectal exciscion) #6 #5 not animal #5 #1 and #2 and #3 and #4 #4 (laparoscop*) or (colectom*) or (restorative proctocolectomy) or (surgery) or (resection) or (Total mesorectal excision) #3 (rect*) or (colorect*) or (colon) or (large intestine) #2 neoplasm* or cancer or tumor or tumour or carcinom* or malignan* or laparoscopy or adenomas #1 random* or blind* or meta‐analysis or placebo*