Table 2.
Serine/glycine concentrations and clinical pathological parameters in PCa
| Characteristics | No. specimens (%) | Serine (μmol/L) | Glycine (μmol/L) | ||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| Median = 17.639 | Median = 54.484 | ||||||
|
|
|
||||||
| <17.639 | ≥17.639 | P value | <54.484 | ≥54.484 | P value | ||
| Histology | |||||||
| Normal | 43 | 42 | 1 | 0.000*** | 34 | 9 | 0.000*** |
| PCa | 66 | 12 | 54 | 20 | 46 | ||
| Age (year) of PCa | |||||||
| <60 | 4 (6.1) | 1 (1.5) | 3 (4.5) | 0.561 | 2 (3.05) | 2 (3.05) | 0.352 |
| ≥60 | 62 (93.9) | 11 (16.7) | 51 (77.3) | 18 (27.3) | 44 (66.7) | ||
| PSA (μg/L) of PCa | |||||||
| Median = 20.67 | |||||||
| <20.67 | 26 (39.4) | 5 (7.6) | 21 (31.8) | 0.553 | 9 (13.6) | 17 (25.8) | 0.364 |
| ≥20.67 | 40 (60.6) | 7 (10.6) | 33 (50.0) | 11 (16.7) | 29 (43.9) | ||
| Gleason score of PCa | |||||||
| <7 | 13 (19.7) | 5 (7.6) | 8 (12.1) | 0.049* | 1 (1.5) | 12 (18.2) | 0.043* |
| ≥7 | 53 (80.3) | 7 (10.6) | 46 (69.7) | 19 (28.8) | 34 (51.5) | ||
Note. PSA: prostate specific antigen; PCa: prostate cancer. Statistical method: χ2 test. The bold entries represent statistically significant differences.
*
P<0.05;
**P<0.01;
***
P<0.001.