Table 1.
Age | Gender | Primary | BRAF status | PFSa (days) | OSb (days) | Disease stage | Treatment response | Type of treatment | |
---|---|---|---|---|---|---|---|---|---|
1 | 60 | Male | CMMc | V600E | 186 | 696 | M1cd | PRe | BRAFif |
2 | 50 | Female | CMM | V600E | 170 | 637 | M1c | PR | BRAFi |
3 | 32 | Male | UKg | V600E | 148 | 248 | M1c | PR | BRAFi |
4 | 40 | Male | CMM | V600E | 101 | 203 | M1c | PR | BRAFi, |
5 | 43 | Female | CMM | V600E | 562 | Alive | M1c | PDh | BRAFi and MEKii |
Progression-free survival (PFS).
Overall survival (OS).
Cutaneous malignant melanoma (CMM).
Cutaneous or, subcutaneous metastases (M1c).
Partial response (PR).
BRAF inhibitor (BRAFi; Dabrafenib/Vemurafenib).
Unknown (UK).
Progressive disease (PD).
MEK inhibitor (MEKi; Binimetinib).