Comparison 20. Minocycline/azelaic acid (min/AA) versus isotretinoin.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of participants with good or very good response after 6 months	1	85	Risk Ratio (M‐H, Random, 95% CI)	0.93 [0.83, 1.03]
2 Reduction in NIL: percentage change from baseline	1	85	Mean Difference (IV, Fixed, 95% CI)	‐14.0 [‐27.80, ‐0.20]
3 Reduction in IL: percentage change from baseline	1	85	Mean Difference (IV, Fixed, 95% CI)	‐8.90 [‐17.67, ‐0.13]