Chiu 1990.
| Methods | Randomised: yes, by random number table. Concealment: method not described. Double‐blind: no. Description of withdrawals/dropouts: no. Length of FU: until discharge. Jadad score: 2/5. | |
| Participants | Country: Taiwan. Diagnosis of bleeding: by endoscopy. Source of bleeding: all confirmed or unconfirmed varices. Endoscopy: performed in all patients prior to randomisation. Diagnosis of cirrhosis: histological or clinical. 54 patients. Child's A = 6%, B = 35%, C = 59%. Alcoholic cirrhosis = 26% | |
| Interventions | Terlipressin versus vasopressin. Rx1: terlipressin 2 mg iv every 4 h for 12 h then if no more bleeding, 1 mg iv every 4 h for another 20 h. R x 2: vasopressin 0.4 U/min iv infusion for 12 h then if no more bleeding, 0.2 U/min for another 20 h. Time from admission to treatment: unknown. Initial sclerotherapy: none. |
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| Outcomes | 1. Mortality at discharge. 2. Failure of initial haemostasis at 24 h. 3. Rebleeding at seven days. 4. Procedures required for haemostasis: NR. 5. Blood transfusions: NR. 6. LOS: NR. | |
| Notes | Source of funding: unknown. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |