Silvain 1993.

Methods	Randomised: yes, by table of random numbers. Concealment: method not described. Double‐blind: no. Description of withdrawals/dropouts: no. Length of FU: 30 days. Jadad score: 2/5.
Participants	Country: France Diagnosis of bleeding: by endoscopy. Source of bleeding: all actively bleeding varices. Endoscopy performed in all patients prior to randomisation. Diagnosis of cirrhosis: histological or clinical. 84 patients with 87 episodes. Child's A = 16%, B = 37%, C = 47%. Alcoholic cirrhosis = 91%.
Interventions	Terlipressin versus octreotide. Rx1: terlipressin 2 mg iv once then 1 mg iv every 4 h for 24 h plus NTG transdermal 10 mg every 12h for 24h. Rx2: Octreotide 25 mcg/h infusion for 12 h then 100 mcg sc at 12 h and 18h. Time from admission to treatment: within 4h. Initial sclerotherapy: none.
Outcomes	1. Mortality at 30 days. 2. Failure of initial haemostasis at 12 h. 3. Rebleeding at 30 days. 4. Procedures required for haemostasis. 5. Blood Transfusions. 6. LOS: NR
Notes	Source of Funding: Government Study was terminated at intermediate analysis because of two major adverse reactions in the terlipressin group.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear