Burgio 2011.

Methods	Two site randomised controlled trial
Participants	143 community dwelling male veterans with over active bladder manifested by urgency and frequent urination, with or without urge incontinence
Interventions	Nurse practitioners implemented behavioural and drug therapies over period of 8 weeks. Behavioural consisted of pelvic floor muscle training, delayed voiding, monitoring with bladder diaries and urge suppression techniques Drug group individually titrated extended release oxybutynin 5 to 30 mg/d
Outcomes	Assessed at baseline and 2 weeks after the fourth and final treatment visit (8 weeks) Primary outcome ‐ post‐treatment 24 hour voiding frequency measured according to 7 day bladder diary. Also measured nocturia, urgency, incontinence Secondary outcomes ‐ Global Perception of Improvement
Notes	Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Stratified according to voiding frequency and presence or absence of incontinence
Allocation concealment (selection bias)	Low risk	Sealed envelopes
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Research assistant blind to treatment group scored bladder diaries