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Fig. 4. Graphical summary of the results from the high-throughput solubility screen – the solubility of the scrambled cage library was tested in six different solvents (5 new solvents, plus PCP). A ‘hit’ was determined to be a cage/solvent combination with a concentration ≥300 mg mL–1 (green); cage–solvent combinations with a concentration between 150 and 300 mg mL–1 in yellow; 150 to 100 mg mL–1 in red; combinations below the 100 mg mL–1 threshold are grey. All combinations involved diamine A. Each potential porous liquid was assigned a name based on the partner scrambling amine used in the HT synthetic screen (A–K, left), plus a number assigned to each solvent/scrambling ratio combination (1–36, bottom); for example, the 3 : 3 scrambling ratio of diamine A with diamine B in solvent 2 is B9; the 2 : 4 scrambling ratio of diamine A with diamine I in solvent 3 is I16, etc.