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. Author manuscript; available in PMC: 2020 Feb 13.
Published in final edited form as: Science. 2018 Dec 20;363(6424):270–275. doi: 10.1126/science.aav3421

Fig. 1. bis-Tetrahydroisoquinoline natural products.

Fig. 1.

Jorumycin (1), ecteinascidin 743 (2), and jorunnamycin A (3). Me, methyl; Ac, acetyl; COAc, pyruvyl; X, oxygen or nitrogen substitution; G, oxygen or carbon substitution; R, generic alkyl substitution.