Skip to main content
. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2019 Dec 26;388:114875. doi: 10.1016/j.taap.2019.114875

Figure 12.

Figure 12.

Antral follicle steroidogenesis. Steroidogenesis occurs in mature antral follicles in the ovary. The conversion from cholesterol to 17β-estradiol requires both theca and granulosa cells in the follicle. Cholesterol and downstream sex steroid hormones are written in the boxes. STAR and enzymes in the pathway are written next to the arrows between the boxes. Up or down arrows next to proteins or hormones in the pathway indicate the increases or decreases in gene expression or hormone levels after 96 hours of culture.