2. Strain, Dose and Schedule of BCG administration.
Krege 1996 | Lamm 1985 | Melekos 1990 | Pagano 1990 | Pinsky 1985 | Yamamoto 1990 | |
Strain | Connaught | Pasteur | Pasteur | Pasteur | Pasteur (Armand Frappier | Tokyo |
weekly dose (mg) | 120 | 120 | 150 | 75 | 120 | 80 |
CFU | not given | not given | 6 x 10 (8) | 4‐5 x 10 (8) | not given | not given |
Duration of instillation (h) | 1 | 2 | 2 | 2 | 2 | 2 |
Schedule | weekly x 6, mnthly x 4 | weekly x 6 | weekly x 8 | weekly x 6, (if no tumour = mthly x 12 then 3 mthly x 3, if tumour present = additional weekly x 6) | weekly x 6 | weekly x 6, every 2 weeks x 6, mthly x 20 |
Concomitant intradermal or percutaneous BCG | 0.5mg | 5mg | no | no | 5 X 10 (7) | no |