Table 2. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Ib-M peptides against E. coli O157: H7.
| Compound | E. coli O157: H7 | |||
|---|---|---|---|---|
| ATCC 43888 | AC 188 | |||
| μM ± S.D. | μM ± S.D. | |||
| MIC | MBC | MIC | MBC | |
| Ib-M1 | 4.7 ± 1.7 | 6.3 ± 0.0 | 1.6 ± 0.0 | 3.7 ± 1.3 |
| Ib-M2 | 4.7 ± 1.7 | 6.8 ± 3.1 | 3.7 ± 1.28 | 4.2 ± 1.6 |
| Ib-M4 | 12.5 ± 0.0 | 22.9 ± 5.1 | 6.3 ± 0.0 | 15.6 ± 10.3 |
| Ib-M5 | 8.3 ± 3.2 | 15.6 ± 7.7 | 4.7 ± 1.7 | 7.3 ± 2.6 |
| Ib-M6 | 9.4 ± 3.4 | 11.5 ± 7.3 | 4.7 ± 1.7 | 10.4 ± 3.2 |
| STP | 9.4 ± 3.4 | 11.5 ± 2.6 | 66.7± 25.8 | 108.3 ± 49.2 |
| GNT | 1.8 ± 0.6 | 4.7 ± 1.7 | 2.3 ± 0.9 | 4.2 ± 1.6 |
Each concentration was evaluated in triplicate in two independent experiments. The results are expressed in terms of the arithmetic average of each group ± standard deviation (S.D.), STP: Streptomycin, GNT: Gentamicin