Table 3. 50% cytotoxic concentrations (CC50) and selectivity index (SI) of Ib-M peptides.
| Compounds | CC50 (μM ± S.D.) | SI | |
|---|---|---|---|
| VERO Cells | E. coli O157: H7 | ||
| ATCC 43888 | AC188 | ||
| Ib-M1 | 395.2 ± 18.3 | 84.1 | 247 |
| Ib-M2 | 197.5 ± 2.4 | 42 | 54.9 |
| Ib-M4 | >400 ± 0.0 | >32 | >63.5 |
| Ib-M5 | 315.3 ± 49.1 | 38 | 67.1 |
| Ib-M6 | 310.9 ± 4.4 | 33.1 | 66.1 |
| STP | >3200 ± 0 | >340.4 | >48 |
| GNT | >3200 ± 0 | >1777.8 | >1391.3 |
Each concentration was evaluated in triplicate in two independent experiments. The results are expressed in terms of the arithmetic average of each group ± standard deviation (S.D). STP: Streptomycin, GNT: Gentamicin.