Fig 11. Phosphorylation of AS160 (pAS160 Thr⁶⁴²) and Akt (pAkt Ser⁴⁷³ and pAkt Thr³⁰⁸) for isolated epitrochlearis and soleus muscles from WT and KO rats.

Paired muscles were incubated in the absence (white bars) or presence (black bars) of insulin (500 μU/ml). AS160 pThr⁶⁴² was not detectable in any of the tissues studied from KO rats (A and B). Data were analyzed by t-test. ^†P<0.01, no insulin versus insulin in WT rats. * P<0.001, no insulin versus insulin in rats with same genotype. Means ± SEM for 6 rats of each genotype.