Table 2. Relative myosin heavy chain isoform composition of skeletal muscles.
%MHC-I | %MHC-IIA | %MHC-IIB | %MHC-IIX | |||||
---|---|---|---|---|---|---|---|---|
WT | KO | WT | KO | WT | KO | WT | KO | |
EDL | 0 | 0 | 13.1 ±0.8 | 12.1 ±0.9 | 57.2 ±3.5 | 58.4 ±1.8 | 29.7 ±3.5 | 29.6 ±1.3 |
EPI | 7.7 ±1.4 | 8.3 ±1.8 | 10.3 ±1.6 | 12.7 ±0.7 | 59.7 ±1.6 | 54.3 ±1.4 | 24.1 ±3.0 | 24.2 ±1.5 |
GAS | 12.8 ±2.1 | 11.6 ±3.4 | 15.8 ±0.9 | 12.4 ±1.5 | 45.3 ±3.5 | 48.9 ±4.9 | 26.1 ±2.8 | 27.0 ±1.6 |
SOL | 89.8 ±2.2 | 89.0 ±2.5 | 10.2 ±2.2 | 11.0 ±2.5 | 0 | 0 | 0 | 0 |
Myosin heavy chain (MHC) isoform reported as relative values (%) for EPI (extensor digitorum longus), EPI (epitrochlearis), GAS (gastrocnemius), and SOL (soleus). Means ± SEM for 6 rats of each genotype: WT = wildtype, and KO = AS160-KO.