Table 4. Hyperinsulinemic euglycemic clamp (HEC).

	WT	KO
Basal blood glucose, mmol/L	6.81 ±0.41	6.13 ±0.24
Clamp blood glucose, mmol/L	7.49 ±0.43*	6.10 ±0.15
Basal plasma insulin, μU/mL	7.21 ±1.65	6.75 ±0.54
Clamp plasma insulin, μU/mL	502.07 ±23.93	500.42 ±16.00
GIR, μmol/kg/min	240.02 ±13.27†	135.87 ±6.98
Clamp GTR, μmol/kg/min	248.06 ±3.15†	162.12 ±12.65
Basal HGP, μmol/kg/min	68.45 ±12.84	57.07 ±5.52
Clamp HGP, μmol/kg/min	8.03 ±10.88	26.24 ±7.32
Suppression of HGP rate, %	84.93 ±20.86	69.13 ±11.04

Glucose infusion rate = GIR. Glucose turnover rate = GTR. Hepatic glucose production = HGP. Means ± SEM for 4 rats of each genotype: WT = wildtype, and KO = AS160-KO.

*P 0.05,

^†P<0.001, WT versus KO.