Table 1. Profile of antiretroviral drug use in the state of Paraná and its distribution per lines of therapy and number of users.
| Antiretroviral drugs | Regimens including the drug | Users per line of therapy | Total users of the drug | |||
|---|---|---|---|---|---|---|
|
| ||||||
| First | Second | Third | Not defined | |||
| NRTI | ||||||
| Lamivudine | 179 | 21,376 | 10,107 | 2,717 | 67 | 34,267 |
| Abacavir | 42 | 284 | 286 | 24 | 7 | 601 |
| Zidovudine | 69 | 2,844 | 2,697 | 132 | 9 | 5,682 |
| Didanosine | 1 | 1 | 1 | |||
| Stavudine | 1 | 2 | 2 | |||
| Tenofovir | 101 | 18,415 | 7,117 | 2,547 | 57 | 28,136 |
| NNRTI | ||||||
| Efavirenz | 41 | 14,195 | 39 | 117 | 1 | 14,352 |
| Etravirine | 37 | 224 | 1 | 225 | ||
| Nevirapine | 19 | 941 | 6 | 10 | 957 | |
| PI | ||||||
| Atazanavir | 55 | 9,404 | 172 | 9,576 | ||
| Darunavir | 91 | 1,042 | 2,720 | 3,762 | ||
| Fosamprenavir | 0 | 0 | ||||
| Indinavir | 0 | 0 | ||||
| Lopinavir + Ritonavir | 14 | 142 | 3 | 145 | ||
| Ritonavir | 143 | 10,186 | 2,884 | 68 | 13,138 | |
| Saquinavir | 0 | 0 | ||||
| Tipranavir | 6 | 1 | 7 | 8 | ||
| FI | ||||||
| Enfuvirtide | 7 | 10 | 10 | |||
| CCR5 | ||||||
| Maraviroc | 27 | 67 | 1 | 68 | ||
| INI | ||||||
| Raltegravir | 29 | 319 | 3 | 63 | 385 | |
| Dolutegravir | 74 | 5,903 | 463 | 835 | 8 | 7,209 |
Results expressed as n.
NRTI: nucleoside analog reverse-transcriptase inhibitor; NNRTI: non-nucleoside reverse-transcriptase inhibitor; Pi: protease inhibitor; FI: fusion inhibitor; CCR5: CCR5 inhibitor; INI: integrase inhibitor.