Table 3. Glutathione results.
rowspan="2"> | >Group 1 | >Group 2 | >Group 3 | >Group 4 | >Group 1 vs. 3§ | >Group 1 vs. 4§ |
Mean±SD | >Mean±SD | >Mean±SD | >Mean±SD | >Mean±SD | >Mean±SD | |
Heart | >77.4±12.6** | >54.1±24.0 | >26.8±6.1††† | >33.4±7.6‡ | ><0.001 | ><0.001 |
Ischemic muscle | >78.3±18.3*** | >53.3±5.9 | >48.9±5.5 | >43.5±6.8 | ><0.001 | ><0.001 |
Kidney | >80.5±12.5*** | >35.6±9.2 | >28.5±6.8 | >26.7±3.6‡ | ><0.001 | ><0.001 |
Liver | >31.5±5.5*** | >19.7±3.6 | >21.8±3.4 | >21.7±3.0 | ><0.001 | ><0.001 |
Blood | >27.3±6.6* | >21.4±4.6 | >15.8±3.0†† | >16.9±2.2‡ | ><0.001 | ><0.001 |
colspan="7">SD: Standard deviation; Passed normality test. The ANOVA test and Tukey’s multiple comparison test were used; Heart, Ischemic muscle, Kidney, liver (nmoL/mg protein) and blood (mg/dL) GSH levels. For paired comparison of sham with Groups 1, 3 and 4 p values are: Group 1 vs. Group 2: * <0.05; ** <0.01; *** <0.001 Group 2 vs. Group 3: † <0.05; †† <0.01; ††† <0.001 Group 2 vs. Group 4: ‡ <0.05; (comparisons without notations and comparisons between group 3 and 4 are statistically not significant [p>0.05]). § P values. Group 1: Control group; Group 2: Sham group; Group 3: Clopidogrel pre-treatment group; Group 4: Rivaroxaban pre-treatment group. |