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. 2018 Sep 16;26(4):528–535. doi: 10.5606/tgkdc.dergisi.2018.16497

Table 3. Hemostatic data.

  Lean body weight group 
(n=50)
Actual body weight group
(n=50)
 
  n % Mean±SD n % Mean±SD p
Heparin therapy (102/IU)
Initial dose 
Additional dose for target ACT
During cardiopulmonary bypass
Total dose
 
 
15
13
 
 
30
26
 
200.1±39.5
 
 
267.9±43.1
 
 
13
26
 
 
0
0
 
295.6±51.1
 
 
354.5±62.1
 
<0.001*
0.656
<0.001*
<0.001*
ACT (sec)
Baseline
After initial dose heparin
Cardiopulmonary bypass login
After protamine
ICU
     
131.9±18.5
473.5±113.8
568.8±144.7
133.0±18.9
145.8±23.4
     
126.7±17.6
540.2±164.9
611.6±140.0
129.6±28.6
161.9±34.4
 
0.140
0.011*
0.067
0.676
0.403
Protamine (102/IU)     276.7±10.1     328.8±24.2 <0.001*
Additional protamine dose in ICU 3 6   8 16   0.110
SD: Standard deviation; ACT: Activated clotting time; ICU: Intensive care unit; * p<0.05.