Table 3. Hemostatic data.
Lean body weight group (n=50) |
Actual body weight group (n=50) |
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n | % | Mean±SD | n | % | Mean±SD | p | |
Heparin therapy (102/IU) Initial dose Additional dose for target ACT During cardiopulmonary bypass Total dose |
15 13 |
30 26 |
200.1±39.5 267.9±43.1 |
13 26 |
0 0 |
295.6±51.1 354.5±62.1 |
<0.001* 0.656 <0.001* <0.001* |
ACT (sec) Baseline After initial dose heparin Cardiopulmonary bypass login After protamine ICU |
131.9±18.5 473.5±113.8 568.8±144.7 133.0±18.9 145.8±23.4 |
126.7±17.6 540.2±164.9 611.6±140.0 129.6±28.6 161.9±34.4 |
0.140 0.011* 0.067 0.676 0.403 |
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Protamine (102/IU) | 276.7±10.1 | 328.8±24.2 | <0.001* | ||||
Additional protamine dose in ICU | 3 | 6 | 8 | 16 | 0.110 | ||
SD: Standard deviation; ACT: Activated clotting time; ICU: Intensive care unit; * p<0.05. |