Table 1. Use of either ZFN or TALEN led to knockout of the Aedes cadherin gene, but ZFN is far more efficient.
Group | Components | Injected embryos | G0 larval survivors (%) | G1 Indel rate (%) |
---|---|---|---|---|
#1 | Aacad ZFN | 741 | 59 (7.9%) | 43/54 (79.6%) |
#2 | AaeTALEN | 793 | 267 (34%) | 4/117 (3.4%) |