Table.
Control | DM | Low-dose | Mid-dose | High-dose | P value | |
Immunoexpression levels | ||||||
iNOS | 1 ± 0.258 | 3 ± 0.378 | 2 ± 0.32 | 1,5 ± 0.32 | 2 ± 0.258 | 0.000 |
eNOS | 3 ± 0.378 | 1 ± 0.258 | 1.5 ± 0.353 | 2 ± 0.378 | 1.5 ± 0.176 | 0.000 |
VEGF | 1 ± 0.231 | 3 ± 0.231 | 1.5 ± 0.258 | 2.5 ± 0.258 | 3 ± 0.378 | 0.000 |
NF-ᴋB | 1 ± 0.231 | 2.75 ± 0.267 | 2.5 ± 0.258 | 1.5 ± 0.231 | 2 ± 0.231 | 0.000 |
TUNEL scores (%) | ||||||
TUNEL-positive cells | 2 ± 0.175% | 4 ± 0.375% | 3 ± 0.312% | 2 ± 0.212% | 3 ± 0.262% | 0.000 |
Groups | SOD activation(% inhibition rate) | MDA levels(nmol/mL) |
Control | 120.15 ± 7.39 | 56.98 ± 8.22 |
DM | 75.37 ± 5.28a | 122.09 ± 8.22a |
Low-dose | 138.81 ± 6.33a,b | 81.4 ± 3.29a,b |
Mid-dose | 97.01 ± 8.44a,b,c | 81.4 ± 6.58a,b |
High-dose | 86.57 ± 2.11a,b | 82.56 ± 1.64a,b |