Table 3.
Groups | Genotypes | Allele A | Allele G | Observed frequency | Expected frequency | P-value | |
NAFLD patients | AA | 120 | 240 | 0 | 120 | 121.08 | 0.2560 |
AG | 25 | 25 | 25 | 25 | 22.84 | ||
GG | 0 | 0 | 0 | 0 | 1.08 | ||
Total | 145 | 265 | 25 | 145 | 145.00 | ||
Controls | AA | 105 | 210 | 0 | 105 | 107.76 | 0.0540 |
AG | 40 | 40 | 40 | 40 | 34.48 | ||
GG | 0 | 0 | 0 | 0 | 2.76 | ||
Total | 145 | 250 | 40 | 145 | 145.00 |
As shown above, the frequencies of either the genotypes or alleles in both groups were in Hardy–Weinberg equilibrium.