Table 3.

Univariate analysis of risk factors of bacteremia in children with FN.

Parameter, n (%)	Bacteremia (+)	Bacteremia (–)	P-value
WBC (/µL) [median (min–max)]	420 (0–3150)	600 (80–26,500)	0.02
Severity of neutropenia at admission <100/mm3100–500/mm3	30 (85.7%)5 (14.2%)	72 (62.6%)43 (37.3%)	0.01
Positivity in peripheral blood culture during previous 3 months, n (%)	14 (40.0%)	23 (20.0%)	0.01
Positivity in central line culture during previous 3 months, n (%)*	15 (42.8%)	16 (13.9%)	<0.0001
Presence of central line*	30 (85.7%)	77 (67.0%)	0.03
Presence of previous FN episode(s)	32 (91.4%)	72 (62.6%)	0.001
Hypotension	6 (17.1%)	0 (0%)	<0.0001
Tachycardia	6 (17.1%)	0 (0%)	<0.0001
Tachypnea	4 (11.4%)	0 (0%)	0.003

FN, febrile neutropenia; WBC, white blood cell count; *, central venous catheter or implantable port.