Table 2.

Current treatment of AD, advantages, and unmet needs.

Current treatment	Unmet needs	New goals
Topical and systemic corticosteroids, calcineurine inhibitors, immunomodulators	Disease flare-ups are seen despite long term usage of today’s available drugs	Minimizing flare-ups, achieving disease free life
Drugs are used for months or years in general	Long term application may not be safe in children (malignancy in calcineurine inhibitors)	Patients should adapt therapy easily in their lives, attaining short term using drugs
Only for eczematous lesions, providing temporary wellbeing, not prevent recurrence and other allergic diseases	Generally proceeds to asthma and allergic rhinitis	Prevention of other allergic disorders with radical treatment strategies
Systemic antihistamines are used for pruritus and give sedation	Pruritus does not cease and is recalcitrant, psychological exhaustion appears frequently due to pruritus	Effective antipruritic drugs
Parents and patients should spend many hours in a day for skin care. In addition, moisturizers and drugs are expensive	Time-consuming and economic burden on families and country economy	Spending shorter time for skin care, cheap and effective alternative treatment options