Table 3.
The relationship between circHIPK3 expression level (as divided into two groups based on the median of ΔCt) in GC tissues with clinicopathological parameters
| Characteristic | Number (#30)(%) | cir_ITCH expression | P-value | |
| Low (#15) | High (#15) | |||
| Gender Male Female | 1614 | 78 | 96 | 0.36 |
| Age (years) ≥70 <70 | 1416 | 213 | 123 | 0.0005** |
| Depth of invasion T2 T3-T4 | 129 | 114 | 015 | 0.50 |
| N classification NX-N0 N1 N2-N3 | 61113 | 555 | 168 | 0.08 |
| M classification MX M0 M1 | 5196 | 573 | 0123 | 0.28(M0 vs. M1) |
| TNM stage I-II III IV | 1686 | 744 | 942 | 0.31 |
| Perineural invasion Negative Positive | 1218 | 510 | 78 | 0.35 |
| Lymphatic invasion Negative Positive | 624 | 213 | 411 | 0.34 |
| Tumor size (cm) ≥5 <5 | 255 | 123 | 132 | 0.50 |
| Tumor grades I II III | 9813 | 744 | 249 | 0.04** |
| Tumor types Diffuse Intestinal | 1416 | 510 | 96 | 0.13 |
* A higher ΔCt value indicates higher expression. ** Statistically significant.