Table 6.
Hypercapnia + Hypoxia Challenge Respiratory Outcomes
| WBP Metrics units | Baseline | 1 WPS | 5 WPS | 11 WPS | ||||
|---|---|---|---|---|---|---|---|---|
| S | T | S | T | S | T | S | T | |
| Frequency breaths/minute | 393 (38) | 397 (39) | 373 (33) | 362 (33) | 387 (33) | 376 (39) | 370 (22) | 369 (24) |
| Tidal Volume ml | 0.65 (0.07) | 0.65 (0.04) | 0.66 (0.07) | 0.67 (0.03) | 0.68 (0.07) | 0.67 (0.05) | 0.76* (0.06) | 0.70* (0.04) |
| Inspiratory Time seconds | 0.07 (0.01) | 0.07 (0.01) | 0.07 (0.01) | 0.08 (0.01) | 0.07 (0.01) | 0.07 (0.01) | 0.07 (0.00) | 0.07 (0.01) |
| Expiratory Time seconds | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) | 0.09 (0.01) |
| Peak Inspiratory Flow ml/second | 14.5 (1.3) | 14.6 (1.6) | 13.6 (1.4) | 13.1 (1.1) | 14.9 (1.2) | 14.1 (1.4) | 16.3* (0.09) | 15.0* (1.4) |
| Minute Ventilation ml/minute | 251 (21) | 257 (24) | 245 (27) | 242 (17) | 258 (19) | 251 (24) | 278* (17) | 258* (24) |
Note: WBP = Whole Body Plethysmography; S = Sham; T = Transection; ml = milliliters; WPS = Weeks Post-Surgery; WBP metric values represent the mean (standard deviation). Bold values with an asterisk (*) denotes statistical significance (p < 0.05) between groups at the individual time point.