Video 1. Comparison between the ‘flat’ tetramer of assembled filaments and the ‘bowed’ tetramer of free octamers.

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Morph comparison between catalytic tetramers of the GTP/ATP/IMP filament assembly interface and the GTP/ATP free octamer. For visualization purposes, we have depicted the complete N-terminus in both conformations, however in the free octamer model, some residues were unresolved (gray). For both models, opposing tetramers, Bateman domains, and active site loops have been hidden from view.