Age |
|
Median (years) |
64 |
Range (years) |
19–86 |
Sex |
No. (%) |
Female |
124 (47.1) |
Male |
139 (52.9) |
Weight |
|
Median (kg) |
80.4 |
Range (kg) |
38–165.8 |
Self-declared race |
No. (%) |
Native American |
1 (0.4) |
Asian |
8 (3) |
Other |
13 (5) |
Black |
15 (5.7) |
Unknown |
26 (9.9) |
White |
200 (76) |
Reason for CYP2C19 genotyping |
No. (%) |
Admitted to hospital for diagnosis workup |
3 (1.1) |
Ambulatory management |
17 (6.5) |
Admitted to hospital for febrile neutropenia |
20 (7.6) |
Admitted to hospital to receive chemotherapy |
223 (84.8) |
CYP2C19 genotyping turnaround time |
|
Median (days) |
3 |
Range (days) |
0–12 |
CYP2C19 genotypes/phenotypes |
No. (%) |
CYP2C19*17/*17‒ultrarapid metabolizer |
5 (1.9) |
CYP2C19*1/*17‒rapid metabolizer |
74 (28.1) |
CYP2C19*1/*1‒normal metabolizer |
105 (39.9) |
CYP2C19*2/*17‒intermediate metabolizer |
23 (8.7) |
CYP2C19*1/*2‒intermediate metabolizer |
49 (18.6) |
CYP2C19*2/*2‒poor metabolizer |
7 (2.7) |
CYP2C19 allele frequencies |
No. (%) |
CYP2C19*1
|
333 (63.3) |
CYP2C19*17
|
107 (20.3) |
CYP2C19*2
|
86 (16.4) |