Skip to main content
. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2019 Nov 1;107(3):563–570. doi: 10.1002/cpt.1641

Table 2.

Percent of patients prescribed voriconazole (VCZ) per the CYP2C19-guided prophylaxis protocol

Patients CYP2C19 genotyped receiving/not receiving VCZ (n=263) No. (%)
 Did not receive VCZ 44 (16.7)
 Received VCZ 219 (83.3)
Reason for VCZ prescribing (n=219) No. (%)
 Treatment 17 (7.8)
 Prophylaxis 202 (92.2)
Followed CYP2C19-guided prophylaxis protocol No. (%)
 All genotype groups (n=202) 176 (87.1)
CYP2C19*1/*17 group (n=58) 46 (79.3)
CYP2C19*17/*17 group (n=5) 4 (80)
Reason for not following the protocol No. (%)
 Weight‒obese dosing 1 (3.9)
 Prior VCZ pharmacokinetics 1 (3.9)
 Patient died before CYP2C19 returned 1 (3.9)
 Elevated liver enzymes 3 (11.5)
 Unknown 6 (23.1)
 Patient discharged from hospital before CYP2C19 returned 14 (53.8)