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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: FASEB J. 2019 Dec 24;34(2):1928–1938. doi: 10.1096/fj.201902116R

Table 1.

Calculation of Blood Neutrophil turnover rate during one decade of an individual’s life. Assumes the half-life of neutrophils in circulation is 1 day (See text for discussion).

Parameter Estimates
Blood volume 5000 ml (A)
Average Neutrophil count 5000 /μl (B)
Circulating Neutrophil pool (CGP) (A × B) 2.5 × 1010 cells (C)
Total Neutrophil Blood Pool (TGBP) 2 × C 5 × 1010 cells (D)
Half-life in Circulation (h) 1 Day
Neutrophil turnover rate per Decade (3650 days) 0.91 × 1014 cells/Decade