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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: FASEB J. 2019 Dec 23;34(2):2326–2343. doi: 10.1096/fj.201902542R

Figure 6.

Figure 6.

(A) Human neutrophils were stimulated with 10μg/ml PHA-E, 10μg/ml GNA or 10μg/ml MMR for indicated time points before lysis and immunoblotting for Syk, Erk1/2 and p38MAPK. (B) Densitometry analysis of p38MAPK phosphorylation at 60 minutes of stimulation normalized to total p38MAPK levels at the same time point. Values shown are relative to Ntx (*, p<0.05, **, p>0.01). (C) Model showing how differential modulation of intracellular signaling cascades downstream of CD11b glycan engagement may regulate different patterns of PMN functional responses.